44 research outputs found
Complex partial synchronization patterns in networks of delay-coupled neurons
We study the spatio-temporal dynamics of a multiplex network of delay-coupled FitzHugh–Nagumo oscillators with non-local and fractal connectivities. Apart from chimera states, a new regime of coexistence of slow and fast oscillations is found. An analytical explanation for the emergence of such coexisting partial synchronization patterns is given. Furthermore, we propose a control scheme for the number of fast and slow neurons in each layer.DFG, 163436311, SFB 910: Kontrolle selbstorganisierender nichtlinearer Systeme: Theoretische Methoden und Anwendungskonzept
Special features of the Be2He fragmentation in emulsion at an energy of 1.2~A~GeV
The results of investigations of the relativistic Be nucleus
fragmentation in emulsion which entails the production of two He fragments of
an energy of 1.2~A~GeV are presented. The results of the angular measurements
of the Be2He events are analyzed.
The BeBe+n fragmentation channel involving the Be decay from
the ground (0) and the first excited (2) states to two
particles is observed to be predominant.Comment: 10 pages, 6 figures, conference: Conference on Physics of Fundamental
Interactions, Moscow, Russia, 5-9 Dec 2005 (Author's translation
Fragmentation of relativistic nuclei in peripheral interactions in nuclear track emulsion
The technique of nuclear track emulsions is used to explore the fragmentation
of light relativistic nuclei down to the most peripheral interactions - nuclear
"white" stars. A complete pattern of therelativistic dissociation of a B
nucleus with target fragment accompaniment is presented. Relativistic
dissociation Be is explored using significant statistics and
a relative contribution of Be decays from 0 and 2 states is
established. Target fragment accompaniments are shown for relativistic
fragmentation N3He+H and Ne5He. The leading role of the
electromagnetic dissociation on heavy nuclei with respect to break-ups on
target protons is demonstrated in all these cases. It is possible to conclude
that the peripheral dissociation of relativistic nuclei in nuclear track
emulsion is a unique tool to study many-body systems composed of lightest
nuclei and nucleons in the energy scale relevant for nuclear astrophysics.Comment: 15 pages, 4 figures, 4 tables, conference: Relativistic nuclear
physics: from Nuclotron to LHC energies, Kiev, June 18-22, 200
Topology of "white" stars in relativistic fragmentation of light nuclei
In the present paper, experimental observations of the multifragmentation
processes of light relativistic nuclei carried out by means of emulsions are
reviewed. Events of the type of "white" stars in which the dissociation of
relativistic nuclei is not accompanied by the production of mesons and the
target-nucleus fragments are considered.
A distinctive feature of the charge topology in the dissociation of the Ne,
Mg, Si, and S nuclei is an almost total suppression of the binary splitting of
nuclei to fragments with charges higher than 2. The growth of the nuclear
fragmentation degree is revealed in an increase in the multiplicity of singly
and doubly charged fragments with decreasing charge of the non-excited part of
the fragmenting nucleus.
The processes of dissociation of stable Li, Be, B, C, N, and O isotopes to
charged fragments were used to study special features of the formation of
systems consisting of the lightest , d, and t nuclei. Clustering in
form of the He nucleus can be detected in "white" stars via the
dissociation of neutron-deficient Be, B, C, and N isotopes.Comment: 20 pages, 3 figures, 9 tables, conference: Conference on Physics of
Fundamental Interactions, Moscow, Russia, 1-5 Mar 2004.(Author's translation
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Erratum to: Functional Analysis of Membrane Proteins Produced by Cell-Free Translation.
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Characterization of the Inflammatory Response in Dystrophic Muscle Using Flow Cytometry
Although mutations of the dystrophin gene are the causative defect in Duchenne muscular dystrophy (DMD) patients, secondary disease processes such as inflammation contribute greatly to the pathogenesis of DMD. Genetic and histological studies have shown that distinct facets of the immune system promote muscle degeneration or regeneration during muscular dystrophy through mechanisms that are only beginning to be defined. Although histological methods have allowed the enumeration and localization of immune cells within dystrophic muscle, they are limited in their ability to assess the full spectrum of phenotypic states of an immune cell population and its functional characteristics. This chapter highlights flow cytometry methods for the isolation and functional study of immune cell populations from muscle of the mdx mouse model of DMD. We include a detailed description of preparing single-cell suspensions of dystrophic muscle that maintain the integrity of cell-surface markers used to identify macrophages, eosinophils, group 2 innate lymphoid cells, and regulatory T cells. This method complements the battery of histological assays that are currently used to study the role of inflammation in muscular dystrophy, and provides a platform capable of being integrated with multiple downstream methodologies for the mechanistic study of immunity in muscle degenerative diseases
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Erratum to: Functional Analysis of Membrane Proteins Produced by Cell-Free Translation.
Renin-angiotensin and kallikrein-kinin systems: a significance in the benign prostatic hyperplasia pathogenesis
Background. Benign prostatic hyperplasia (BPH) is the most common disease in older men. BPH pathophysiology is poorly understood. Although, it is known that the transmission of androgenergic signals and the reactivity of prostate's stroma as well as inflammatory factors are known to be the main pathophysiological mechanisms. In this regard, it is of interest to study the activity of enzymes and their inhibitors of the renin-angiotensin and kallikrein-kinin systems in BPH.Objectives. The study of new molecular mechanisms of the BPH pathogenesis.Materials and methods. The activity of the angiotensin-converting enzyme (ACE), the kallikrein-like activity and the prekallikrein content were determined. The total arginine-esterase activity was the inhibitory activity of the a1-proteinase inhibitor and a2-macroglobulin in the prostate secretion in men with BPH.A sharp increase of ACE activity in BPH leads to the accumulation of angiotensin II in the prostate secretion. A consequence of the activation of ACE in prostate secretion is a decrease in the content of bradykinin. An increase of the a1-proteinase inhibitor suppressing activity in prostate secretion at BPH indicates an increase in leukocyte degranulation activity during the development of the inflammatory process.Results. A sharp increase of ACE activity in BPH leads to the accumulation of angiotensin II in the prostate secretion. A consequence of the activation of ACE in prostate secretion is a decrease in the content of bradykinin. An increase of the a1-proteinase inhibitor suppressing activity in prostate secretion at BPH indicates an increase in leukocyte degranulation activity during the development of the inflammatory process.Conclusion. Metabolic basis for the BPH development can be mediated by impaired metathesis of angiotensin II and bradykinin in the prostate